What is Atrial Fibrillation?

Atrial fibrillation is a relatively common abnormal heart rhythm where the atria beat quickly, irregularly, and unevenly.

Atrial fibrillation always has some degree of atrial-ventricular (AV) block with a 2:1 pattern meaning the rate of the ventricles is usually 150 beats per minute while the atria beat at 300 beats per minute. In other words, every other atrial beat reaches the ventricle. AF is an atrial rate of greater than 300 bpm with an irregular transmission of electrical impulses through to the ventricles, causing a fast, irregular heart beat. this differs from atrial flutter, which causes a fast, regular heart rhythm.

This arrhythmia impairs blood flow out of the heart (cardiac output) and promotes clot (thrombus) formation.

Animation of Atrial Fibrillation

How does atrial fibrillation occur?

Blood remains in the chamber that leads to clot formation.

In atrial fibrillation, chaotic electrical signals travel across the heart in an abnormal way. Abnormal electrical pathways produce irregular heartbeats and rhythms known as arrhythmias.

Arrhythmias occur when other areas of the heart, other than the SA node, begin sending out their own impulses and take over the pacemaker function of the SA node. The sites that take over could be from any area of the atria, AV node, or ventricles.

The rapid fibrillation of the atria does not allow the complete filling of the ventricles, that pumps blood out to the entire body. Symptoms of atrial fibrillation such as lightheadedness or dizziness may be felt.

Also, some amount of blood remains in the chamber that leads to clot formation.

What are the types?

Atrial fibrillation can occur in different patterns.

These include:

Paroxysmal (intermittent) atrial fibrillation: recurrent (2 or more) episodes, spontaneously terminates and converts back to normal sinus rhythm within a week, lasting for less than 24 hours, typically related to a reversible cause.
Persistent atrial fibrillation: occurs in episodes, does not spontaneously convert back to sinus rhythm and is unrelated to a reversible cause.
Permanent atrial fibrillation: the heart is always in atrial fibrillation and is unrelated to a reversible cause.

What are the causes?

Atrial fibrillation can be due to abnormalities or diseases of the heart, or by diseases elsewhere in the body affecting the heart. Atrial fibrillation may occur after open heart surgery or substance abuse.

Heart abnormalities and diseases include:

Coronary artery disease (decreased blood supply to the heart) or atherosclerosis
High blood pressure
Heart attack
Cardiomyopathy and congestive heart failure
Rheumatic fever and pericarditis (inflammation of the heart)
Abnormalities of the heart valves, especially mitral stenosis and mitral regurgitation
Hypertrophy (enlarged heart)
Sick sinus syndrome

Diseases elsewhere in the body affecting the heart:

Pulmonary embolism (blood clot in lung)
Chronic obstructive pulmonary disease (COPD) and emphysema
Sleep apnea

Substance abuse:

Consuming large amounts of alcohol (binge drinking)
Cocaine, amphetamines, diet pills, caffeine, or cold medicines
Carbon monoxide intoxication


First week following open heart surgery



Congenital heart defects (heart defect from birth)

Who is at risk?

The following are at risk of developing atrial fibrillation:

Increasing age
Men are at more risk of developing atrial fibrillation than women
Family history of atrial fibrillation
Drinking alcohol or binge drinking
Atrial fibrillation is greatest when an underlying heart disease is associated with left atrial enlargement, left ventricular or biventricular failure
Heart failure patients and COPD patients
Other chronic conditions including thyroid disorders and sleep apnea

What are the symptoms?

Some patients may be unaware of their heart beating abnormally. Although characteristic symptoms include:

Palpitations (pounding sensation in the chest)
Chest pain
Shortness of breath

Dizziness, light-headedness
Intolerance to exercise
Swelling of the legs or abdomen

What are the complications?

The complications of atrial fibrillation include:

Syncope (fainting)
Heart failure
Thrombus (clot formation)

When should I seek medical care?

If you experience symptoms of atrial fibrillation, call your physician.
If you have already been diagnosed and being treated for atrial fibrillation, seek medical help at the hospital as soon as possible if you have the following symptoms:

Severe chest pain
Feeling faint or light-headed
Have an actual episode of fainting

How is it diagnosed?

The diagnosis of atrial fibrillation will be based on your history, physical examination, and certain tests.

1. Patient history

Most patients will give a history of characteristic symptoms like palpitations, dizziness, fatigue, shortness of breath, etc.

2. Physical Examination

You will be examined for signs of atrial fibrillation including:

Rapid, irregular, fast pulse
Heart rate of 100-175 (Normal heart rate = 60-100)
Normal to low blood pressure
Varying heart sounds heard over chest

Chest X-ray- a simple test performed in our office showing the size and shape of the heart.

3. Tests

Certain tests can be performed to determine the cause and severity of your condition including:

Blood tests- to check potassium and thyroid hormone levels
Electrocardiogram- this is a very useful and simple test that records the electrical activity of the heart and reveals atrial fibrillation. Also shows signs of heart attack, conduction abnormalities, hypertrophy, and electrolyte imbalances.

Chest X-ray- a simple test performed in our office showing the size and shape of the heart. Also reveals the presence of fluid in the lungs.
Echocardiogram (ECHO) – a noninvasive test performed in our office to determine the size and function of the heart’s chambers and the structure and function of the heart valves.
24-Hour Holter monitor- records the electrical events of the heart during your normal daily activities. This is useful in detecting evidence of arrhythmias.
Event monitor- If symptoms of arrhythmia are infrequent and do not occur within 24 hours, an event recorder may be ordered for you for up to 30 days.
Stress test- determines how well the heart works during exercise.

How is it treated?

Atrial fibrillation treatment goals include restoring the heart to normal rhythm, regulating heart rate, preventing blood clot formation, and treating the underlying cause.

This is done by the use of medications and procedures.

1. Medications

Some medications are used to slow an irregularly fast heart beat. These decrease the heart rate by slowing the conduction of impulses through the AV node.

These drugs include:

Beta Blockers
Calcium channel blockers

Medications are used to reduce the frequency and duration of atrial fibrillation and prevent future episodes.

These include:


Medications are used to prevent the formation of blood clots.

These drugs include:



Cardioversion– Cardioversion is a medical procedure that restores a normal heart rhythm in people with certain types of abnormal heartbeats (arrhythmias). atrial fibrillation is sensitive to a low electrical energy direct-current (DC) or medical cardioversion (using an antiarrhythmic drug). DC cardioversion converts atrial fibrillation into a normal sinus rhythm with a high success rate. Cardioversion may need to be delayed until starting treatment with an anticoagulant. This medication is usually given for 3-4 weeks, allowing preexisting clots to resolve. A transesophageal echocardiogram (TEE) is an alternative way of delaying cardioversion, if no blood clots are present, cardioversion may be started. A mild sedative is first given, pads are applied over the chest, and then the heart will be shocked into the correct rhythm.

Catheter radiofrequency ablation- is a hospital procedure done to destroy areas on the heart that are causing irregular heart rhythms. A thin flexible tube is inserted into a blood vessel to access the heart. Heat is applied to the tip of the catheter to permanently destroy small areas of abnormal heart tissue. The damaged tissue is no longer capable of generating electrical impulses. A pacemaker may be placed after this procedure.

Pacemaker or Implantable Cardiac Defibrillator (ICD) – a small implantable device used to regulate the heart rate and rhythm. Therefore, the heart contracts in a regular way. An ICD shocks the heart out of the dangerous rhythm.

Animation of Catheter radiofrequency ablation

What is the prognosis?

Atrial fibrillation can be controlled with treatment.

With treatment, many patients do well.
However, atrial fibrillation tends to return and get worse. It may come back even with treatment.

How can I prevent this?

Atrial fibrillation can not always be prevented, but there are ways of reducing the risk of developing atrial fibrillation.

Leading a healthy lifestyle may reduce the chance of coronary artery disease, which can cause atrial fibrillation.

Some ways you can do this is by:

No smoking!
Be physically active. Engage in moderate physical activity for at least 30 minutes a day
Eat nutritious foods low in cholesterol and fats
Maintain a BMI below 25
Control high blood pressure, cholesterol, and sugar